High - conductance states and A - type K + channels are potential regulators 2 of the conductance - current balance triggered by HCN channels
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چکیده
Abbreviated title: High-conductance state and HCN channel physiology 19 20 Number of words in abstract: 244 21 Number of figures: 11 22 Number of tables: 1 23 24 25
منابع مشابه
High-conductance states and A-type K+ channels are potential regulators of the conductance-current balance triggered by HCN channels.
An increase in the hyperpolarization-activated cyclic nucleotide-gated (HCN) channel conductance reduces input resistance, whereas the consequent increase in the inward h current depolarizes the membrane. This results in a delicate and unique conductance-current balance triggered by the expression of HCN channels. In this study, we employ experimentally constrained, morphologically realistic, c...
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AIMS The hyperpolarization-activated cyclic nucleotide-gated (HCN) current I(f)/I(HCN) is generally thought to be carried by Na(+) and K(+) under physiological conditions. Recently, Ca(2+) influx through HCN channels has indirectly been postulated. However, direct functional evidence of Ca(2+) permeation through I(f)/I(HCN) is still lacking. METHODS AND RESULTS To possibly provide direct evid...
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تاریخ انتشار 2014